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50μL/100μL

Catalog No : AR1002

Reactivity : Human; Mouse; Rat;

Applications : WB;IHC;IF;IP;ELISA

Target : PARP1

Fields : >>Base excision repair;>>NF-kappa B signaling pathway;>>Apoptosis;>>Necroptosis;>>Diabetic cardiomyopathy

Gene Name : PARP1

Protein Name : Poly [ADP-ribose] polymerase 1

Human Gene Id : 142

Human Swiss Prot No : P09874

Mouse Swiss Prot No : P11103

Specificity : endogenous

Formulation : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Source : Monoclonal, rabbit, IgG, Kappa

Dilution : IHC 1:200-1000,WB 1:500-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

Purification : Protein A

Storage Stability : -20°C

Molecularweight : 25kD

Observed Band : 25kD

This gene encodes a chromatin-associated enzyme, poly(ADPribosyl)transferase, which modifies various nuclear proteins by poly(ADPribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]

應用：WB;IHC;IF;IP;ELISA
稀釋比例：IHC 1:200-1000,WB 1:500-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

避免反復凍融