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50μL/100μL

Catalog No : AR1003

Reactivity : Mouse;

Applications : WB;IHC;IF;IP;ELISA

Target : CD86

Fields : >>Cell adhesion molecules;>>Toll-like receptor signaling pathway;>>Intestinal immune network for IgA production;>>Type I diabetes mellitus;>>Kaposi sarcomaassociated herpesvirus infection;>>Transcriptional misregulation in cancer;>>Autoimmune thyroid disease;>>Systemic lupus erythematosus;>>Rheumatoid arthritis;>>Allograft rejection;>>Graft-versus-host disease;>>Viral myocarditis

Gene Name : CD86 CD28LG2

Protein Name : CD86 Human

Gene Id : 942

Human Swiss Prot No : P42081

Mouse Gene Id : 12524

Mouse Swiss Prot No : P42082

Specificity : endogenous

Formulation : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Source : Monoclonal, rabbit, IgG, Kappa

Dilution : IHC 1:200-1000,WB 1:500-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

Purification : Protein A 

Storage Stability : -20°C

Molecularweight : 60-80kD

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]

應(yīng)用：WB;IHC;IF;IP;ELISA
稀釋比例：IHC 1:200-1000,WB 1:500-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

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