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50μL/100μL

Catalog No : AR1035

Reactivity : Human; Mouse; Rat;

Applications : WB;IHC;IF;IP;ELISA

Target : MITF

Fields : >>Mitophagy - animal;>>Osteoclast

differentiation;>>Melanogenesis;>>Pathways in cancer;>>Transcriptional

misregulation in cancer;>>Melanoma

Gene Name : MITF

Protein Name : Microphthalmia-associated transcription factor

Human Gene Id : 4286

Human Swiss Prot No O75030

Mouse Gene Id : 17342

Mouse Swiss Prot No :Q08874

Specificity : endogenous

Formulation : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Source : Monoclonal, rabbit, IgG, Kappa

Dilution : IHC 1:200-500,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

Purification : Protein A

Storage Stability : -20°C

Molecularweight : 58kD

Observed Band : 58kD

Cell Pathway : Melanogenesis;Pathways in cancer;Melanoma;

This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

應(yīng)用：WB;IHC;IF;IP;ELISA
稀釋比例：IHC 1:200-500,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP
1:50-200

避免反復(fù)凍融