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50μL/100μL

Catalog No :AR1037

Reactivity : Human; Mouse; Rat;

Applications : WB;IHC;IF;IP;ELISA

Target : CD8

Fields : >>Cell adhesion molecules;>>Antigen processing and presentation;>>Hematopoietic cell lineage;>>T cell receptor signaling pathway;>>Yersinia infection;>>Primary immunodeficiency

Gene Name : CD8A MAL

Protein Name : CD8 a

Human Gene Id : 925

Human Swiss Prot No :P01732

Specificity : endogenous

Formulation : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Source : Monoclonal, rabbit, IgG, Kappa

Dilution :IHC 1:200-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

Purification : Protein A

Storage Stability : -20°C

Molecularweight : 26kD

Observed Band : 35kD

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T  lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

應用：WB;IHC;IF;IP;ELISA
稀釋比例：IHC 1:200-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP
1:50-200

避免反復凍融