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50μL/100μL

Catalog No : AR1040

Reactivity : Human;Mouse;Rat;

Applications : WB;IHC;IF;IP;ELISA

Target : Catalase

Fields : >>Tryptophan metabolism;>>Glyoxylate and dicarboxylate metabolism;>>Metabolic pathways;>>Carbon metabolism;>>FoxO signaling pathway;>>Peroxisome;>>Longevity regulating pathway;>>Longevity regulating pathway - multiple species;>>Amyotrophic lateral sclerosis;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species

Gene Name : CAT

Protein Name : Catalase

Human Gene Id : 847

Human Swiss Prot No :P04040

Mouse Swiss Prot No :P24270

Specificity : endogenous

Formulation : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Source : Monoclonal, rabbit, IgG, Kappa

Dilution : IHC 1:200-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

Purification : Protein A

Storage Stability : -20°C

Molecularweight : 60kD

Observed Band : 60kD

Cell Pathway :Tryptophan metabolism;Methane metabolism;Amyotrophic lateral sclerosis (ALS)

This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009],

應(yīng)用： WB;IHC;IF;IP;ELISA
稀釋比例： IHC 1:200-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP
1:50-200

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