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50μL/100μL

Catalog No : AR1043

Reactivity : Mouse; Rat;

Applications : WB;IHC;IF;IP;ELISA

Target : UCP1

Fields : >>PPAR signaling pathway;>>Apelin signaling pathway;>>Thermogenesis;>>Huntington disease

Gene Name : UCP1 SLC25A7 UCP

Protein Name : Mitochondrial brown fat uncoupling protein 1 (UCP 1) (Solute carrier family 25 member 7) (Thermogenin)

Human Gene Id : 7350

Human Swiss Prot No :P25874

Mouse Swiss Prot No :P12242

Rat Swiss Prot No : P04633

Specificity : endogenous

Formulation : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Source : Monoclonal, rabbit, IgG, Kappa

Dilution : IHC 1:200-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

Purification : Protein A

Storage Stability : -20°C

Molecularweight : 33kD

Observed Band : 33kD

Cell Pathway : PPAR;Huntington's disease;

Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq, Jul 2008],

應(yīng)用： WB;IHC;IF;IP;ELISA
稀釋比例： IHC 1:200-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP
1:50-200

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