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50μL/100μL

Catalog No : AR1047

Reactivity : Human;

Applications : WB;IHC;IF;IP;ELISA

Target : CD105(Endoglin)

Gene Name : ENG END

Protein Name : Endoglin (CD antigen CD105)

Human Gene Id : 2022

Human Swiss Prot No :P17813

Specificity : endogenous

Formulation : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Source : Monoclonal, rabbit, IgG, Kappa

Dilution : IHC 1:100-200,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

Purification : Protein A

Storage Stability : -20°C

Molecularweight : 70kD

Observed Band : 95kD

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]

應(yīng)用：WB;IHC;IF;IP;ELISA
稀釋比例： IHC 1:100-200,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP
1:50-200

避免反復(fù)凍融