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50μL/100μL

Catalog No : AR1048

Reactivity : Human; Mouse;

Applications : WB;IHC;IF;IP;ELISA

Target : MMP-13

Fields : >>IL-17 signaling pathway;>>Relaxin signaling pathway;>>Parathyroid hormone synthesis, secretion and action

Gene Name : MMP13

Protein Name : Collagenase 3

Human Gene Id : 4322

Human Swiss Prot No :P45452

Mouse Swiss Prot No :P33435

Specificity : endogenous

Formulation : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Source : Monoclonal, rabbit, IgG, Kappa

Dilution :IHC 1:100-500,WB 1:500-2000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

Purification : Protein A

Storage Stability : -20°C

Molecularweight : 60kD

Observed Band : 60kD

Cell Pathway : Angiogenesis

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016],

應用： WB;IHC;IF;IP;ELISA
稀釋比例： IHC 1:100-500,WB 1:500-2000,IF 1:200-1000,ELISA 1:5000-20000,IP
1:50-200

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