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產(chǎn)品中心抗體
Cyclin E1 rabbit mAb
  • 產(chǎn)品信息: Cyclin E1兔單克隆抗體
  • 產(chǎn)品編號(hào): AR1049
  • 產(chǎn)品規(guī)格: 50μL/100μL
  • 產(chǎn)品保存條件: -20℃
  • 產(chǎn)品保質(zhì)期: 1年
  • 產(chǎn)品運(yùn)輸條件: 干冰運(yùn)輸
  • 目錄價(jià): 1288/2328
  • 貨期: 1-2周
商品詳情
【產(chǎn)品包裝】
50μL/100μL
【產(chǎn)品特點(diǎn)】
Catalog No : AR1049

Reactivity : Human; Mouse; Rat;

Applications : WB;IHC;IF;IP;ELISA

Target : Cyclin E1

Fields :>>Cell cycle;>>Oocyte meiosis;>>p53 signaling pathway;>>PI3K-Akt signaling pathway;>>Cellular senescence;>>Cushing syndrome;>>Hepatitis B;>>Measles;>>Human papillomavirus infection;>>Human T-cell leukemia virus 1 infection;>>Epstein-Barr virus infection;>>Pathways in cancer;>>Viral carcinogenesis;>>MicroRNAs in cancer;>>Prostate cancer;>>Small cell lung cancer;>>Gastric cancer

Gene Name : CCNE1

Protein Name : G1/S-specific cyclin-E1

Human Gene Id : 898

Human Swiss Prot No :P24864

Mouse Gene Id : 12447

Mouse Swiss Prot No :Q61457

Rat Swiss Prot No : P39949

Specificity : endogenous

Formulation : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Source : Monoclonal, rabbit, IgG, Kappa

Dilution : IHC 1:400-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

Purification : Protein A

Storage Stability : -20°C

Molecularweight : 47kD

Observed Band : 47kD

Cell Pathway : Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;Oocyte meiosis;p53;Pathways in cancer;Prostate cancer;Small cell lung cancer

【產(chǎn)品介紹】
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in

【使用方法】
應(yīng)用: WB;IHC;IF;IP;ELISA
稀釋比例: IHC 1:400-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP
1:50-200
【注意事項(xiàng)】
避免反復(fù)凍融
020-89449936/19303062859
  • [email protected]
  • 廣州市海珠區(qū)廣州國(guó)際生物島標(biāo)產(chǎn)一期辦公區(qū)一棟102-104單元
友情鏈接: ATCC DSMZ Cellosaurus JCRB 中國(guó)典型培養(yǎng)物保藏中心 中國(guó)國(guó)家實(shí)驗(yàn)細(xì)胞資源共享服務(wù)平臺(tái)
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