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50μL/100μL

Catalog No : AR1058

Reactivity : Human; Mouse; Rat;

Applications : WB;IF;IP;ELISA

Target : NOX4

Fields : >>AGE-RAGE signaling pathway in diabetic complications;>>Alcoholic liver disease;>>Alzheimer disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species

Gene Name : NOX4 RENOX

Protein Name :NADPH oxidase 4 (EC 1.6.3.-) (Kidney oxidase-1) (KOX-1) (Kidney superoxide producing NADPH oxidase) (Renal NAD(P)H-oxidase)

Human Gene Id : 50507

Human Swiss Prot No :Q9NPH5

Mouse Swiss Prot No :Q9JHI8

Rat Swiss Prot No : Q924V1

Specificity : endogenous

Formulation : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Source : Monoclonal, rabbit, IgG, Kappa

Dilution : WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

Purification : Protein A

Storage Stability : -20°C

Molecularweight : 67kD

Observed Band : 67kD

This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009],

應(yīng)用： WB;IF;IP;ELISA
稀釋比例： WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

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