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50μL/100μL

Catalog No : AR1059

Reactivity : Human; Mouse; Rat;

Applications : WB;IHC;IF;IP;ELISA

Target : Neuropilin

Fields : >>Axon guidance;>>Human T-cell leukemia virus 1 infection;>>Coronavirus disease - COVID-19

Gene Name : NRP1

Protein Name : Neuropilin-1

Human Gene Id : 8829

Human Swiss Prot No :O14786

Mouse Gene Id : 18186

Mouse Swiss Prot No :P97333

Rat Gene Id : 246331

Rat Swiss Prot No : Q9QWJ9

Specificity : endogenous

Formulation : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Source : Monoclonal, rabbit, IgG, Kappa

Dilution : IHC 1:200-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

Purification : Protein A

Storage Stability : -20°C

Molecularweight : 103kD

Observed Band : 135kD

Cell Pathway : Axon guidance

This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

應用：WB;IHC;IF;IP;ELISA
稀釋比例： IHC 1:200-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP
1:50-200

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