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50μL/100μL

Catalog No : AR1062

Reactivity : Human; Mouse; Rat;

Applications : WB;IHC;IF;IP;ELISA

Target : HXK II

Fields : >>Glycolysis / Gluconeogenesis;>>Fructose and mannose metabolism;>>Galactose metabolism;>>Starch and sucrose metabolism;>>Amino sugar and nucleotide sugar metabolism;>>Neomycin, kanamycin and gentamicin biosynthesis;>>Metabolic pathways;>>Carbon metabolism;>>Biosynthesis of nucleotide sugars;>>HIF-1 signaling pathway;>>Insulin signaling pathway;>>Type II diabetes mellitus;>>Carbohydrate digestion and absorption;>>Shigellosis;>>Central carbon metabolism in cancer

Gene Name : HK2

Protein Name : Hexokinase-2

Human Gene Id : 3099

Human Swiss Prot No :P52789

Mouse Gene Id : 15277

Mouse Swiss Prot No :O08528

Rat Gene Id : 25059

Rat Swiss Prot No : P27881

Specificity : endogenous

Formulation : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Source : Monoclonal, rabbit, IgG, Kappa

Dilution :IHC 1:200-400,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

Purification : Protein A

Storage Stability : -20°C

Molecularweight : 87kD

Observed Band : 100kD

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009]

應(yīng)用： WB;IHC;IF;IP;ELISA
稀釋比例： IHC 1:200-400,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP
1:50-200

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