商品詳情
【產(chǎn)品包裝】
50μL/100μL
【產(chǎn)品特點】
Catalog No : A1069
Reactivity : Human;Mouse;Rat;
Applications : WB;IHC;IF;IP;ELISA
Target : GCLM
Fields : >>Cysteine and methionine metabolism;>>Glutathione metabolism;>>Metabolic pathways;>>Biosynthesis of cofactors;>>Ferroptosis
Gene Name : GCLM
Protein Name : Glutamate--cysteine ligase regulatory subunit
Human Gene Id : 2730
Human Swiss Prot No :P48507
Mouse Gene Id : 14630
Mouse Swiss Prot No :O09172
Rat Gene Id : 29739
Rat Swiss Prot No : P48508
Specificity : endogenous
Formulation : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source : Monoclonal, rabbit, IgG, Kappa
Dilution : IHC 1:200-1:500,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200,
Purification : Protein A
Storage Stability : -20°C
Observed Band : 31kD
【產(chǎn)品介紹】
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],
【使用方法】
應用: WB;IHC;IF;IP;ELISA
稀釋比例: IHC 1:200-1:500,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA 1:5000-1:20000,IP1:50-1:200,
【注意事項】
避免反復凍融