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50μL/100μL

Catalog No : AR1075

Reactivity : Human; Mouse; Rat;

Applications : WB;IHC;IF;IP;ELISA

Target : TBP/TATA Binding Protein

Fields : >>Basal transcription factors;>>Huntington disease;>>Spinocerebellar ataxia;>>Human papillomavirus infection;>>Human T-cell leukemia virus 1 infection;>>Viral carcinogenesis

Gene Name : TBP

Protein Name : TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)

Human Gene Id : 6908

Human Swiss Prot No :P20226

Mouse Swiss Prot No :P29037

Specificity : endogenous

Formulation : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Source : Monoclonal, rabbit, IgG, Kappa

Dilution :IHC 1:400-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

Purification : Protein A

Storage Stability : -20°C

Molecularweight : 38kD

Observed Band : 38kD

Cell Pathway : Basal transcription factors;Huntington's disease;

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA bin

應(yīng)用： WB;IHC;IF;IP;ELISA
稀釋比例： IHC 1:400-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP
1:50-200

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