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50μL/100μL

Catalog No : AR1090

Reactivity : Human;Mouse;Rat;

Applications : WB;IHC;IF;IP;ELISA

Target : NF-H

Fields : >>Amyotrophic lateral sclerosis;>>Pathways of neurodegeneration - multiple diseases

Gene Name : NEFH

Protein Name : Neurofilament heavy polypeptide

Human Gene Id : 4744

Human Swiss Prot No :P12036

Mouse Swiss Prot No :P19246

Specificity : endogenous

Formulation : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Source : Monoclonal, rabbit, IgG, Kappa

Dilution : IHC 1:200-1:1000,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200,

Purification : Protein A

Storage Stability : -20°C

Molecularweight : 110kD

Observed Band : 180-200kD

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]

應(yīng)用：WB;IHC;IF;IP;ELISA
稀釋比例： IHC 1:200-1:1000,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA
1:5000-1:20000,IP 1:50-1:200,

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