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50μL/100μL

Catalog No : AR1093

Reactivity : Human;Mouse;Rat;

Applications : WB;IHC;IF;IP;ELISA

Target : LRP1

Fields : >>Cholesterol metabolism;>>Alzheimer disease;>>Malaria

Gene Name : LRP1

Protein Name : Prolow-density lipoprotein receptor-related protein 1

Human Gene Id : 4035

Human Swiss Prot No :Q07954

Mouse Gene Id : 16971

Mouse Swiss Prot No :Q91ZX7

Specificity : endogenous

Formulation : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Source : Monoclonal, rabbit, IgG, Kappa

Dilution : IHC 1:200-1:1000,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Purification : Protein A

Storage Stability : -20°C

Molecularweight : 85kD

Observed Band : 85kD

his gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015]

應(yīng)用： WB;IHC;IF;IP;ELISA
稀釋比例： IHC 1:200-1:1000,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA
1:5000-1:20000,IP 1:50-1:200

避免反復(fù)凍融