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50μL/100μL

Catalog No : AR1095

Reactivity : Human;Mouse;Rat;

Applications : WB;IHC;IF;IP;ELISA

Target : FAK

Fields : >>Endocrine resistance;>>ErbB signaling pathway;>>Chemokine signaling pathway;>>PI3K-Akt signaling pathway;>>Axon guidance;>>VEGF signaling pathway;>>Focal adhesion;>>Leukocyte transendothelial migration;>>Regulation of actin cytoskeleton;>>Growth hormone synthesis, secretion and action;>>Bacterial invasion of epithelial cells;>>Shigellosis;>>Yersinia infection;>>Amoebiasis;>>Human cytomegalovirus infection;>>Human papillomavirus infection;>>Human immunodeficiency virus 1 infection;>>Pathways in cancer;>>Transcriptional misregulation in cancer;>>Proteoglycans in cancer;>>Chemical carcinogenesis - reactive oxygen species;>>Small cell lung cancer;>>Lipid and atherosclerosis;>>Fluid shear stress and atherosclerosis

Gene Name : PTK2

Protein Name : Focal adhesion kinase 1

Human Gene Id : 5747

Human Swiss Prot No :Q05397

Mouse Gene Id : 14083

Mouse Swiss Prot No :P34152

Rat Gene Id : 25614

Rat Swiss Prot No : O35346

Specificity : endogenous

Formulation : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Source : Monoclonal, rabbit, IgG, Kappa

Dilution : IHC 1:400-1:1000,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Purification : Protein A

Storage Stability : -20°C

Molecularweight : 119kD

Observed Band : 119kD

protein tyrosine kinase 2(PTK2) Homo sapiens This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined. [provided by RefSeq, Oct 2015],

應用：WB;IHC;IF;IP;ELISA
稀釋比例： IHC 1:400-1:1000,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA
1:5000-1:20000,IP 1:50-1:200

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