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50μL/100μL

Catalog No : AR1097

Reactivity : Human; Mouse; Rat;

Applications : WB;IHC;IF;IP;ELISA

Target : SIRT3

Fields : >>Nicotinate and nicotinamide metabolism;>>Metabolic pathways;>>Central carbon metabolism in cancer

Gene Name : SIRT3

Protein Name : NAD-dependent protein deacetylase sirtuin-3 mitochondrial

Human Gene Id : 23410

Human Swiss Prot No :Q9NTG7

Mouse Swiss Prot No :Q8R104

Specificity : endogenous

Formulation : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Source : Monoclonal, rabbit, IgG, Kappa

Dilution : IHC 1:200-1:1000,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Purification : Protein A

Storage Stability : -20°C

Molecularweight : 44kD

Observed Band : 28kD

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008],

應(yīng)用： WB;IHC;IF;IP;ELISA
稀釋比例： IHC 1:200-1:1000,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA
1:5000-1:20000,IP 1:50-1:200

避免反復(fù)凍融